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赛诺菲CEO韩保罗:企业级AI转型将在2026年重塑制药行业

Paul Hudson
2026-02-12

AI驱动的工具也在重塑研发的经济逻辑。

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赛诺菲首席执行官韩保罗。图片来源:courtesy of Sanofi

在今年的达沃斯世界经济论坛上,AI成为讨论的核心议题。越来越多的人已经认识到,它对创新与增长所产生的影响。我相信,在未来数月,各行各业的公司都会证明:AI并非一时的投机热潮,而是持久的变革引擎,它正在从根本上重塑我们的工作方式。

在赛诺菲(Sanofi),AI已从早期实验阶段,转变为基础设施中的关键组成部分。如今,它支持我们的研发决策、供应链与制造流程,更重要的是,支撑我们发现与开发药物的方式。任何成功将AI落地的企业,都会面临技能缺口与不确定性等挑战,但解决之道在于将AI深度嵌入团队与系统之中,使其成为持续生产力与创新的关键可靠来源。

展望2026年及以后,关键在于企业级规模的落地实施,即从AI实验探索,转向将其作为企业运作的核心。这将是AI投机的终结点,也将是AI成为增长根本驱动力的开始。随着越来越多组织进入这一阶段,关于泡沫的讨论,已经让位于AI在多个领域中展现的长期价值证据——包括由AI发现的新药、优化供应链与制造体系,以及依托新技术实现的预防性医疗。

AI驱动药物研发的新时代

根据波士顿咨询公司(Boston Consulting Group)的一份报告,生成式AI有潜力将早期药物研发周期缩短25%以上。

在赛诺菲,我们已经看到这一趋势带来的显著成果。通过将机器学习与数据整合能力结合实验室研究,我们在一年内发现了10个全新的药物靶点。AI已不再只是辅助研发工作,而是在主动塑造决策流程。我们在召开药物开发委员会会议时,会先由AI智能体评估一款候选药物是否应进入下一临床试验阶段。关键在于,这个智能体并非简单给出“是”或“否”的答案,而是对每一项决策进行完整的情境分析。它会将该资产的前景与其他在研项目进行对比,并评估其相对于赛诺菲其他资本用途的机会成本。这是一个有力的案例,说明AI让药物研发不仅更快速,而且更智能。

这种转型并不仅限于实验室。AI还在解决药物研发中最顽固的难题之一:临床试验招募。AI驱动的患者招募工具,可将临床试验入组率提升65%。借助AI,我们能够通过扫描电子病历、临床记录与化验结果,自动筛选符合条件的患者,从而更精准地匹配复杂的试验标准。同时,我们还能实时判断某个临床试验中心的入组进展是否低于预期,并将资源转向进展更快的中心。过去需要数月才能完成招募的试验,如今可在数天或数周内找到合适人选。

除了加速靶点发现与临床试验招募流程,AI驱动的工具也在重塑研发的经济逻辑。通过加快早期药物发现并生成科学洞见,AI有望将相关成本降低约50%。这些变化将重新定义哪些类型的药物具备商业可行性。未来一年,尤其是在精准医疗领域,我们可以期待关键突破变得更具规模化和可及性。近期多项研究指出,在AI、多组学技术以及前所未有的数据基础设施支持下,精准医疗正从高度定制化靶向治疗,转向面向大规模人群的普惠医疗模式。

构建下一代供应链与制造体系

AI识别供应链脆弱性的能力几乎无可匹敌。借助更高水平的可视化与实时追踪能力,AI系统能够以前所未有的方式洞察库存状况与产品流向。

在赛诺菲,AI驱动的供应链管理已帮助公司规避了3亿美元的收入风险,并提前预测到80%的低库存风险。通过扩大数据获取范围、提升跨部门透明度,企业能够及时作出更明智的决策。其影响是切实可见的:已有68%的供应链企业整合了AI以增强可追溯性与透明度,运营效率因此提升22%。未来几年,随着 AI进一步融入全球供应网络,这些效益还将持续加速显现。

除了提升供应链的可视化与预测能力,AI也正在重塑药品制造方式。它为制造流程提供端到端支持,包括提高效率、改善产品质量与安全性,以及通过实时监测确保稳定、可靠的产出。根据麦肯锡(McKinsey & Company)的分析,AI驱动的数据分析能够显著提高产出率,不仅有助于患者更快获得关键药物,也能提升制造运营的成本效率与可持续性。

推进预防性与预测性医疗

预防医学的下一个前沿是依托远程患者监测与数字化工具,实现早期干预。一项涵盖 1,100余例患者诊疗案例的研究发现,远程患者监测可将住院率降低近60%。在慢性病管理领域,可穿戴设备、症状追踪应用以及环境传感器的结合,正展现出变革性潜力。针对慢性阻塞性肺病(COPD)患者,一项整合上述工具的数字化项目在预测病情加重方面实现了94%的敏感度与90.4%的特异度,使临床医生能够在危机发生前介入。这类整合型数字治疗模式,正在减少脆弱人群的急诊就诊与住院率。随着AI加速制药与医疗行业的进程,我们在更早阶段进行发现、预测与干预的能力也将持续提升。

预防医学的未来,将由疫苗、治疗手段、数据与智能监测的融合所定义。通过将科学创新与AI驱动的洞见相结合,我们有机会推动医疗模式从“被动治疗”转向“主动、持续的防护”。这将带来更好的治疗效果、更低的成本,并最终大规模改变患者生活。

我们正步入一个由AI驱动企业各项职能的新时代。2026年,制药行业的AI转型有望进一步提速,我们将持续推进改变患者命运的药物研发。随着AI能力的不断扩展,我们已经看到讨论的重点已经从对“泡沫”的担忧,转向了对企业驱动的长期价值的关注。最终留下的,可能不是炒作,而是持续增长与深层变革。(财富中文网)

本文作者韩保罗自2019年9月起担任赛诺菲首席执行官。此前,他于2016年至2019年出任诺华制药首席执行官。在加入诺华之前,曾就职于阿斯利康,担任多个高管职务,包括阿斯利康美国总裁及北美区执行副总裁。职业生涯早期,他在葛兰素史克英国公司以及赛诺菲-信达博英国公司担任销售和市场营销岗位。

Fortune.com上发表的评论文章中表达的观点,仅代表作者本人的观点,不代表《财富》杂志的观点和立场。

译者:刘进龙

审校:汪皓

在今年的达沃斯世界经济论坛上,AI成为讨论的核心议题。越来越多的人已经认识到,它对创新与增长所产生的影响。我相信,在未来数月,各行各业的公司都会证明:AI并非一时的投机热潮,而是持久的变革引擎,它正在从根本上重塑我们的工作方式。

在赛诺菲(Sanofi),AI已从早期实验阶段,转变为基础设施中的关键组成部分。如今,它支持我们的研发决策、供应链与制造流程,更重要的是,支撑我们发现与开发药物的方式。任何成功将AI落地的企业,都会面临技能缺口与不确定性等挑战,但解决之道在于将AI深度嵌入团队与系统之中,使其成为持续生产力与创新的关键可靠来源。

展望2026年及以后,关键在于企业级规模的落地实施,即从AI实验探索,转向将其作为企业运作的核心。这将是AI投机的终结点,也将是AI成为增长根本驱动力的开始。随着越来越多组织进入这一阶段,关于泡沫的讨论,已经让位于AI在多个领域中展现的长期价值证据——包括由AI发现的新药、优化供应链与制造体系,以及依托新技术实现的预防性医疗。

AI驱动药物研发的新时代

根据波士顿咨询公司(Boston Consulting Group)的一份报告,生成式AI有潜力将早期药物研发周期缩短25%以上。

在赛诺菲,我们已经看到这一趋势带来的显著成果。通过将机器学习与数据整合能力结合实验室研究,我们在一年内发现了10个全新的药物靶点。AI已不再只是辅助研发工作,而是在主动塑造决策流程。我们在召开药物开发委员会会议时,会先由AI智能体评估一款候选药物是否应进入下一临床试验阶段。关键在于,这个智能体并非简单给出“是”或“否”的答案,而是对每一项决策进行完整的情境分析。它会将该资产的前景与其他在研项目进行对比,并评估其相对于赛诺菲其他资本用途的机会成本。这是一个有力的案例,说明AI让药物研发不仅更快速,而且更智能。

这种转型并不仅限于实验室。AI还在解决药物研发中最顽固的难题之一:临床试验招募。AI驱动的患者招募工具,可将临床试验入组率提升65%。借助AI,我们能够通过扫描电子病历、临床记录与化验结果,自动筛选符合条件的患者,从而更精准地匹配复杂的试验标准。同时,我们还能实时判断某个临床试验中心的入组进展是否低于预期,并将资源转向进展更快的中心。过去需要数月才能完成招募的试验,如今可在数天或数周内找到合适人选。

除了加速靶点发现与临床试验招募流程,AI驱动的工具也在重塑研发的经济逻辑。通过加快早期药物发现并生成科学洞见,AI有望将相关成本降低约50%。这些变化将重新定义哪些类型的药物具备商业可行性。未来一年,尤其是在精准医疗领域,我们可以期待关键突破变得更具规模化和可及性。近期多项研究指出,在AI、多组学技术以及前所未有的数据基础设施支持下,精准医疗正从高度定制化靶向治疗,转向面向大规模人群的普惠医疗模式。

构建下一代供应链与制造体系

AI识别供应链脆弱性的能力几乎无可匹敌。借助更高水平的可视化与实时追踪能力,AI系统能够以前所未有的方式洞察库存状况与产品流向。

在赛诺菲,AI驱动的供应链管理已帮助公司规避了3亿美元的收入风险,并提前预测到80%的低库存风险。通过扩大数据获取范围、提升跨部门透明度,企业能够及时作出更明智的决策。其影响是切实可见的:已有68%的供应链企业整合了AI以增强可追溯性与透明度,运营效率因此提升22%。未来几年,随着 AI进一步融入全球供应网络,这些效益还将持续加速显现。

除了提升供应链的可视化与预测能力,AI也正在重塑药品制造方式。它为制造流程提供端到端支持,包括提高效率、改善产品质量与安全性,以及通过实时监测确保稳定、可靠的产出。根据麦肯锡(McKinsey & Company)的分析,AI驱动的数据分析能够显著提高产出率,不仅有助于患者更快获得关键药物,也能提升制造运营的成本效率与可持续性。

推进预防性与预测性医疗

预防医学的下一个前沿是依托远程患者监测与数字化工具,实现早期干预。一项涵盖 1,100余例患者诊疗案例的研究发现,远程患者监测可将住院率降低近60%。在慢性病管理领域,可穿戴设备、症状追踪应用以及环境传感器的结合,正展现出变革性潜力。针对慢性阻塞性肺病(COPD)患者,一项整合上述工具的数字化项目在预测病情加重方面实现了94%的敏感度与90.4%的特异度,使临床医生能够在危机发生前介入。这类整合型数字治疗模式,正在减少脆弱人群的急诊就诊与住院率。随着AI加速制药与医疗行业的进程,我们在更早阶段进行发现、预测与干预的能力也将持续提升。

预防医学的未来,将由疫苗、治疗手段、数据与智能监测的融合所定义。通过将科学创新与AI驱动的洞见相结合,我们有机会推动医疗模式从“被动治疗”转向“主动、持续的防护”。这将带来更好的治疗效果、更低的成本,并最终大规模改变患者生活。

我们正步入一个由AI驱动企业各项职能的新时代。2026年,制药行业的AI转型有望进一步提速,我们将持续推进改变患者命运的药物研发。随着AI能力的不断扩展,我们已经看到讨论的重点已经从对“泡沫”的担忧,转向了对企业驱动的长期价值的关注。最终留下的,可能不是炒作,而是持续增长与深层变革。(财富中文网)

本文作者韩保罗自2019年9月起担任赛诺菲首席执行官。此前,他于2016年至2019年出任诺华制药首席执行官。在加入诺华之前,曾就职于阿斯利康,担任多个高管职务,包括阿斯利康美国总裁及北美区执行副总裁。职业生涯早期,他在葛兰素史克英国公司以及赛诺菲-信达博英国公司担任销售和市场营销岗位。

Fortune.com上发表的评论文章中表达的观点,仅代表作者本人的观点,不代表《财富》杂志的观点和立场。

译者:刘进龙

审校:汪皓

At Davos this year, AI was a key pillar of discussion. Increasingly, people recognize the impact it is already having on innovation and growth. I believe that we will see in the months ahead companies in all sectors proving that AI is not a speculative moment in time but a durable engine of transformation that’s fundamentally reshaping how we work.

At Sanofi, AI has shifted from experimentation to becoming a vital part of our infrastructure. It now powers our R&D decisions, our supply chain and manufacturing processes, and most importantly how we discover and develop medicines. All businesses that have implemented AI in an impactful way face challenges, such as skills gaps and uncertainty, but you move beyond that by embedding AI deeply into teams and systems. This enables AI to become a key, reliable source of sustained productivity and innovation.

The critical factor in 2026 and beyond will be enterprise-scale implementation, shifting from experimenting with AI to operationalizing it at the core of how companies work. This will be the tipping point where AI speculation ends, and where it becomes a fundamental driver of growth. As more organizations reach this stage, debates about bubbles have already given way to evidence of durable, long-term value in areas including new drugs discovered by AI, optimized supply chain and manufacturing and preventative medicine powered by new technologies.

The New Era of AI-Driven Drug Development

According to a Boston Consulting Group report, generative AI has the potential to accelerate early-stage drug breakthroughs, reducing timelines by 25% or more.

At Sanofi, we are already seeing this materialize with dramatic results. Combining machine learning and data integration with lab research has helped us discover 10 completely news drug targets in just one year. AI is no longer just assisting R&D efforts, it is actively shaping decision-making. Our drug development committee meetings begin with an AI agent’s assessment of whether a drug should advance to the next trial phase. Crucially, the agent does not simply give a yes or no answer but fully contextualizes each decision. It compares the asset’s prospects against others in development and assesses its opportunity cost relative to alternative uses of Sanofi’s capital. This is a powerful example of how AI is making drug development not only faster, but smarter.

This transformation doesn’t stop in the lab. AI is also addressing one of the most persistent obstacles in drug development: clinical trial recruitment. AI-powered patient recruitment tools improve clinical trial enrollment rates by 65%. Through AI we can now automate patient eligibility through scanning electronic health records, clinical notes and lab results. This enables higher accuracy in matching patients to complex criteria in trials. We can also determine in real time if a clinical trial site is not enrolling as expected and move our efforts to sites that are progressing more rapidly. Trials that once required months to recruit now find the right patients in days or weeks.

Beyond accelerated target discovery and clinical trial recruitment processes, AI-driven tools are transforming the economics of R&D. Its accelerating early-stage drug discovery and generating scientific insights that can reduce costs by an estimated 50%. These shifts are poised to reshape what kinds of medicines become viable. In the year ahead, we can expect key breakthroughs, particularly in precision medicine, to become more scalable and accessible. Recent reviews underscore that thanks to AI, multi-omics and an unprecedented data infrastructure precision medicine is moving from bespoke targeting to large-scale, population-level care models.

Building the Next Generation of Supply Chains & Manufacturing

AI’s ability to detect vulnerabilities in supply chains is unparalleled. Through enhanced visibility and real-time tracking, AI systems provide unprecedented insights into inventory levels and product movement.

At Sanofi, AI-driven supply chain management has enabled the company to avoid $300 million in revenue risk and predict 80% of low inventory risks before they occur. By expanding access to data and increasing transparency across functions, organizations can make better informed decisions in a timely manner. The impact is tangible: 68% of supply chain organizations have already integrated AI to enhance traceability and visibility, resulting in a substantial 22% increase in operational efficiency. These gains will only accelerate over the next few years as AI becomes further embedded in global supply networks.

Beyond visibility and forecasting in supply chain operations, AI is reshaping the way we approach the manufacturing of medicines. AI is providing end-to-end support in manufacturing through enhancing efficiency, product quality and safety and enabling real-time monitoring that ensures consistent, reliable output. According to McKinsey, AI-driven analytics can significantly maximize yield which not only ensures patients are receiving critical medicines faster but also improves the cost and sustainability of manufacturing operations.

Advancing Preventative and Predictive Care

The next frontier in prevention is early intervention supported by remote patient monitoring and digital tools. One study of more than 1,100-plus patient encounters found that remote patient monitoring cut hospitalizations by nearly 60%. For chronic diseases, the combination of wearables, symptom-tracking apps and environmental sensors is proving to be transformative. In COPD patients, a digital program integrating these tools achieved 94% sensitivity and 90.4% specificity in predicting exacerbations enabling clinicians to intervene before crises occur. These types of integrated digital therapeutic models are reducing emergency visits and admissions for vulnerable populations. As AI accelerates timelines across the pharma and healthcare industry, our ability to discover, predict and intervene earlier will only expand.

The future of prevention will be defined by the convergence of vaccines, therapeutics, data and intelligent monitoring. By pairing scientific innovation with AI-driven insights, we have the opportunity to shift the healthcare approach from reactive treatment to proactive, continuous protection. The result will be improved outcomes, reduced costs and ultimately transformation of patient lives at scale.

We are in a new era powered by AI across business functions. 2026 promises accelerated momentum of AI-powered transformation in the pharmaceutical industry as we continue to pursue the discovery of life-changing medicines for patients. As AI capabilities continue to scale, we’ve already seen the conversation shift away from concerns about a bubble and toward the evidence of durable, enterprise-driven value. What is likely to remain is not hype but sustained growth and meaningful transformation.

Paul Hudson has been CEO of Sanofi since September 2019. Previously, he was CEO of Novartis Pharmaceuticals from 2016 to 2019. Prior to Novartis, he worked for AstraZeneca, where he held several increasingly senior positions and served as president, AstraZeneca US and executive vice president, North America. He began his career in sales and marketing roles at GlaxoSmithKline UK and Sanofi-Synth?labo UK.

The opinions expressed in Fortune.com commentary pieces are solely the views of their authors and do not necessarily reflect the opinions and beliefs of Fortune.

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