福奇感染新冠，服用辉瑞药物后症状反而加重
美国总统的首席医疗顾问安东尼·福奇博士于6月28日称，他在服用帮助其康复的抗病毒药物Paxlovid之后，新冠症状出现了反复。
他表示，用药后的症状比最初的症状更加严重。
据彭博社（Bloomberg）报道，81岁的福奇在出席《外交政策》杂志（Foreign Policy）举办的全球健康论坛（Global Health Forum）活动时说：“服用Paxlovid五天之后，我连续三天抗原检测结果都变成了阴性。但在第四天，为了万无一失，我又进行了一次检测。结果复阳了。”
然后他开始服用Paxlovid的第二个疗程，这一次出现的症状“比第一次更加严重”。福奇表示，他到6月28日还感觉“相当良好”。
Paxlovid被批准用于治疗高风险成年人新冠肺炎患者。它获得了美国食品与药品管理局（U.S. Food and Drug Administration）的紧急使用授权。
福奇因为年龄较大开了Paxlovid处方，这反而增加了新冠的严重后果对他的影响。据彭博社报道，福奇已经完成免疫，并接种了两剂加强针。
今年6月初，该药物的生产商辉瑞（Pfizer）宣布，将停止招募更多低入院治疗和死亡风险的新冠患者试用这款药物。彭博社报道称，研究未能证明该药可以从统计上显著减少症状或住院与死亡比例。
美国疾病控制与预防中心（U.S. Centers for Disease Control and Prevention）在5月发布了一份与“新冠反弹”有关的健康建议，又被称为“Paxlovid反弹”。
该建议书称：“短暂出现症状可能是某些人感染SARS-CoV-2（导致新冠肺炎的病毒）的自然过程的一部分，与服用Paxlovid和疫苗接种情况无关。”
美国疾病控制与预防中心在建议书中表示，没有证据证明反弹病例需要接受额外治疗。根据这份指导意见，目前尚不确定，福奇为什么会第二轮服用Paxlovid。
该中心建议，服用Paxlovid后症状反复的患者需要再次隔离五天。（财富中文网）
译者：刘进龙
审校：汪皓
美国总统的首席医疗顾问安东尼·福奇博士于6月28日称，他在服用帮助其康复的抗病毒药物Paxlovid之后，新冠症状出现了反复。
他表示，用药后的症状比最初的症状更加严重。
据彭博社（Bloomberg）报道，81岁的福奇在出席《外交政策》杂志（Foreign Policy）举办的全球健康论坛（Global Health Forum）活动时说：“服用Paxlovid五天之后，我连续三天抗原检测结果都变成了阴性。但在第四天，为了万无一失，我又进行了一次检测。结果复阳了。”
然后他开始服用Paxlovid的第二个疗程，这一次出现的症状“比第一次更加严重”。福奇表示，他到6月28日还感觉“相当良好”。
Paxlovid被批准用于治疗高风险成年人新冠肺炎患者。它获得了美国食品与药品管理局（U.S. Food and Drug Administration）的紧急使用授权。
福奇因为年龄较大开了Paxlovid处方，这反而增加了新冠的严重后果对他的影响。据彭博社报道，福奇已经完成免疫，并接种了两剂加强针。
今年6月初，该药物的生产商辉瑞（Pfizer）宣布，将停止招募更多低入院治疗和死亡风险的新冠患者试用这款药物。彭博社报道称，研究未能证明该药可以从统计上显著减少症状或住院与死亡比例。
美国疾病控制与预防中心（U.S. Centers for Disease Control and Prevention）在5月发布了一份与“新冠反弹”有关的健康建议，又被称为“Paxlovid反弹”。
该建议书称：“短暂出现症状可能是某些人感染SARS-CoV-2（导致新冠肺炎的病毒）的自然过程的一部分，与服用Paxlovid和疫苗接种情况无关。”
美国疾病控制与预防中心在建议书中表示，没有证据证明反弹病例需要接受额外治疗。根据这份指导意见，目前尚不确定，福奇为什么会第二轮服用Paxlovid。
该中心建议，服用Paxlovid后症状反复的患者需要再次隔离五天。（财富中文网）
译者：刘进龙
审校：汪皓
Chief presidential medical adviser Dr. Anthony Fauci said on June 28 that he experienced a so-called Paxlovid rebound after he took the antiviral to aid his recovery from COVID.
The symptoms he developed after he took the pill were more severe than those he had initially, he said.
“After I finished the five days of Paxlovid, I reverted to negative on an antigen test for three days in a row,” Fauci, 81, said during an event at Foreign Policy’s Global Health Forum, Bloomberg reported. “And then on the fourth day, just to be absolutely certain, I tested myself again. I reverted back to positive.”
He then began a second course of Paxlovid when symptoms emerged “much worse than the first go-around,” he said. Fauci said he was feeling “reasonably good” as of June 28.
Paxlovid is a pill approved for treatment of COVID-19 in high-risk adults. It has emergency-use authorization from the U.S. Food and Drug Administration.
Fauci was prescribed Paxlovid owing to his advanced age, which puts him at greater risk for a severe outcome from COVID. He is fully vaccinated and twice boosted, Bloomberg reported.
Earlier June Pfizer, which manufactures the medication, announced that it would stop adding new participants to a trial of the drug among COVID patients at low risk of hospitalization and death. The study failed to demonstrate that the drug reduced symptoms, or hospitalizations and deaths in a statistically significant way, according to Bloomberg.
The U.S. Centers for Disease Control and Prevention in May issued a health advisory regarding “COVID-19 rebound,” also known as “Paxlovid rebound.”
But “a brief return of symptoms may be part of the natural history of SARS-CoV-2 (the virus that causes COVID-19) infection in some persons, independent of treatment with Paxlovid and regardless of vaccination status,” the advisory stated.
There is no evidence that additional treatment is needed for rebound cases, the CDC said in the advisory. It is unclear why Fauci took a second course of Paxlovid, in light of this guidance.
Patients who rebound after taking Paxlovid will need to isolate again for five days, according to the CDC.
